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Statistical Concepts Used in Demographic and Epidemiologic Studies

 

Adjusted rate: A rate that has taken into account influences on a crude rate, such as differences in age composition of the population.

Adjustment: A summarizing procedure for a statistical measure in which the effects of differences in composition of the populations being compared have been minimized by statistical methods. Adjustment often is performed on rates or relative risks, commonly because of differing age distributions in populations that are being compared. Examples are adjustment by regression analysis and by standardization. The mathematical procedure commonly used to adjust rates for age differences is direct or indirect standardization.

Age-specific rate: Number of events occurring to a specified age group per 100,000 population of the specified age group (for example, age-specific fertility rate, death rate, marriage rate, illiteracy rate, school enrollment rate, etc.).

Average: A measure of the central tendency in a distribution, indicated by such statistics as the median and arithmetic mean; the distribution around the average can be narrow or broad.

Average daily census: The average number of patients in a facility on any day divided by the number of days in the reporting calendar year.

Average length of stay: The average number of days of service rendered to each inpatient before discharge from an institution during a given period, which is typically a calendar year.

Case fatality rate: The number of patients dying from a specific condition, divided by the number developing the condition per 1,000 affected persons. For hospital patients this statistic may be the rate of patients dying prior to discharge from hospital.

Cause-specific death rate: Number of deaths from a specific cause per 100,000 population.

Confidence interval: The range of values that has a probability of including the true value for the population; a 95% confidence interval includes the true value for the population 95% of the time.

Crude rate: The rate of actual demographic or vital event that is based on an entire population, generally the annual births or deaths per 100,000 total population. Referred to as "crude rates" since they do not take into account a population's age structure.

General fertility rate (GFR): The number of live births per 100,000 women age 15-44 years in a given year.

Infant mortality: Cumulative number of deaths to babies, born alive, before they reach their first birthday.

Life table: Statistical tool typically used to portray expectation of life at various ages. Also provides information on numbers of individuals who survive to various ages, median age at death, age-specific death rates, and the probability of dying at certain ages.

Mean: The arithmetic average of a set of values. It is calculated as the sum of the values divided by the number of values.

Median: The value in an ordered set of values above and below which there are an equal number of values; the 50th percentile.

Mode: The most frequent number in a set of numbers.

Percentage occupancy for staffed beds: The ratio of the number of inpatient days of care to the number of bed days open during the year for staffed beds, expressed as a percentage.

Percentage occupancy for licensed beds: The ratio of the number of inpatient days of care to the number of bed days open during the year for licensed beds, expressed as a percentage.

Population per facility: A measure relating the number of people residing in a specifically defined geographic area (county, region, or state) by the number of short term nonfederal hospitals in that specified area.

Prevalence: The number of existing cases of a disease or health condition in a population at some designed time. Point Prevalence is the number of person ill divided by total number in the population group at a time point; Period Prevalence is the number of person ill divided by the average population during a time period.

Probability: A measure ranging from zero to one, based on the relative frequency of a specific event occurring in a sequence of total trials of events.

Proportion: A type of ratio in which the denominator includes the numerator; for example the ratio of females to the total population.

Randomization: Governed by chance, as opposed to deterministic. Allocation of individuals to groups, e.g., for experimental and control regimens by chance selection.

Range: The distance between the smallest and largest numbers in a set of numbers.

Rate: The frequency of a demographic event in a specified period of time divided by the population at risk of the event.

Rate of natural increase: The difference (±) between the crude birth rate and the crude death rate in a given population per year. If all children born live to reproduce, any number of births greater than 1 per biological parent can potentially result in population increase.

Ratio: The relation of one population subgroup to another subgroup, or to the total population; the denominator of a ratio may or may not include the numerator. If the denominator includes the numerator, it is a special type of ratio known as a proportion.

Reference population: The standard against which a population that is being studied can be compared.

Sex-ratio: A measure relating the number of males to females in a population or age group.

Stable population: A population that has constant fertility and mortality rates, no migration, and consequently a fixed age distribution and constant growth rate.

Standardization: A set of techniques used to remove as far as possible the effects of differences in age or other confounding variables, when comparing two or more populations. For example, Age standardization, often called “age adjustment”, is one of the key tools used to control for the changing age distribution, and thereby to make meaningful comparison of vital rates over time and between groups.

Stationary population: A stable population that has a zero growth rate with constant numbers of births and deaths each year.

Statistical cut-off: Point in time by which records of vital events for a specific year must be received in order to be included in the statistical analyses for that year.

Statistical significance: Used to evaluate the likelihood that chance variability may be considered an explanation for observed results. An appropriate mathematical test of statistical significance is calculated to determine the "p value", which is the probability that the observed results may be due to chance alone. If the p value is less than an arbitrarily chosen value, commonly selected as 0.05, the findings are accepted as statistically significant at the 5 percent level. This indicates there is less than 5 percent probability that the observed results are due to chance alone.

Total fertility rate (TFR): The average number of children a woman will have assuming that the current age-specific birth rates will remain constant throughout her childbearing years (15-44). 

References:

Alderson, Michael. An Introduction to Epidemiology. Great Britain : MacMillan Press, 1976.

Haupt, Arthur and Thomas T. Kane. Population Handbook. Washington , D.C. : Population Reference Bureau, Inc., 1991.

Last, John M. A Dictionary of Epidemiology. Second Edition. New York : Oxford Press, 1988.

Nam , Charles B. Understanding Population Change. Itasca: Peacock Publishers, Inc. 1994.

Friis, Robert H and Thomas A. Sellers. Epidemiology for Public Health Practice (2nd ed). Gaithersburg : Aspen Publication, 1999.

Last Updated: 10/10/2006.